Filtration
Optimize production with fast, reliable insights into particle size, shape, and morphology
Challenges
in the Filtration Processes
Inconsistent incoming particle sizes
Impact filtration efficiency and the filtrate quality/purity
Clogging and Fouling
Presence of fine or agglomerates that cause filter clogging, reducing efficiency and throughput
Flow and Permeability
Particles with irregular shapes can negatively affect the filtration rate and permeability
Material Loss
Inconsistent particle sizes or poor dispersion can lead to higher material loss during filtration
Particle Concentration
Difficulty in accurately measuring particle concentration in liquids, particularly for fine particles under 150 µm, which are critical to the filtration process
How ParticleTech
Helps
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Precise Size Distribution
Measures particle size distribution with high precision, ensuring consistent powder characteristics and reliable performance in end-use applications
Detection & Quantification
Identifies and quantifies the fraction of agglomerates, helping to optimize drying conditions and reduce product defects
Particle Structure Differentiation
Differentiates between hollow, collapsed, and intact particles to assess drying efficiency and improve overall product quality
Advanced Morphology Analysis
Provides morphology analysis to detect process deviations early, enabling proactive adjustments to minimize unwanted product variations
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Fast Process Feedback
Delivers rapid feedback to support timely process adjustments, enhancing batch-to-batch consistency and operational control
Quantification
Accurately quantifies fines or dust particles (smaller than 5–10 µm), helping to minimize allergen exposure and meet safety standards
Application
Areas
Optimization of Spray Drying Parameters
To achieve desired particle properties and ensure the quantity of fines/dust is within the limits
Formation of Agglomerates and Deposits
Help monitor and control the formation of both of agglomerates and deposits
Powder Bulk Density and Flowability
Evaluating powder bulk density and flowability for improved packaging and handling
Uniform Particle Morphology
Ensuring uniform particle morphology for enhanced dissolution and performance
Quality Control of Spray-dried Powders
Performing quality control of spray-dried powders before final product formulation
WorkFlow
of a Practical Analysis
1.
Minimal sample preparation
Analyze directly using the ParticleTech CombiCell
2.
Setup & Run
No calibration or cleaning required, ensuring seamless operation
3.
Results after just 2 Minutes
Allowing for real-time monitoring and optimization
Business Benefits
of using ParticleTech for Filtration
- Provides Fast, Comprehensive Particle Characterization with Minimal Effort
- Enables Real-Time Process Optimization with Rapid Feedback Loops
- Eliminates Human Subjectivity compared to Traditional Microscopy-based Methods
- Detects and Quantifies Defects that Impact Product Performance
- Applicable to Various Spray-Dried Powders, including Food, Pharmaceuticals, and Chemicals
